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1.
Rev. Odontol. Araçatuba (Impr.) ; 38(2): 46-50, maio-ago. 2017. ilus, graf
Article in Portuguese | LILACS, BBO | ID: biblio-876090

ABSTRACT

A citopatologia é uma técnica que propicia diagnósticos rápidos para lesões em mucosas, além de ser bastante acessível do ponto de vista econômico. Na odontologia, pode ser um bom exame auxiliar no diagnóstico de lesões bucais, principalmente lesões infecciosas, bem como na detecção precoce do câncer de boca. Objetivos: estabelecer a técnica de citopatologia no laboratório de Patologia Oral do Instituto de Saúde de Nova Friburgo da UFF, bem como avaliar dados demográficos e discutir os diagnósticos citopatológicos desses pacientes. Métodos: foram selecionados 90 pacientes atendidos na clínica de Estomatologia da UFF-NF com lesões orais que tinham indicação para realização da citopatologia oral. Após obtenção de dados demográficos, a coleta de material foi feita, seguida da realização do esfregaço em duas lâminas de vidro. Resultados: Dos 90 pacientes, 54 (60%) eram mulheres e 36 (40%) homens. A idade dos pacientes variou de 30 a 82 anos, com média de 56,60 anos. Desses pacientes, 23 (26%) declararam-se tabagistas, 27 (30%) declararam-se etilistas e 77 (86%) eram usuários de próteses dentárias. Os esfregaços dos 90 pacientes foram diagnosticados de acordo com as classes de Papanicolaou, sendo a maioria, 84 pacientes (93%), diagnosticada como Classe II. Desses 84 pacientes, 34 (40,4%) apresentaram candidíase. Conclusão: após a realização deste trabalho, além da técnica de citopatologia ser estabelecida, pode-se perceber que os esfregaços inflamatórios e apresentando fungo foram predominantes, o que demonstra a boa capacidade diagnóstica da técnica de citopatologia para lesões infecciosas(AU)


Objectives: to establish the technique of cytopathology in the laboratory of Oral Pathology of the Institute of Health of Nova Friburgo of the UFF, as well as to evaluate demographic data and to discuss the cytopathological diagnoses of these patients. Methods: 90 patients attended at the Stomatology clinic of the UFF-NF with oral lesions that had been indicated for oral cytopathology were selected. After obtaining demographic data, the material was collected, followed by the smearing on two glass slides. Results: Of the 90 patients, 54 (60%) were women and 36 (40%) were men. The patients' ages ranged from 30 to 82 years, with a mean of 56.60 years. Of these patients, 23 (26%) declared themselves smokers, 27 (30%) declared themselves alcoholics and 77 (86%) were users of dental prostheses. The smears of the 90 patients were diagnosed according to the classes of Papanicolau, being the majority, 84 patients (93%), diagnosed as Class II. Of these 84 patients, 34 (40.4%) presented candidiasis. Conclusion: after this work, besides the cytopathology technique was established, it can be noticed that the inflammatory smears and presenting fungus were predominant, which demonstrates the good diagnostic capacity of the cytopathology technique for infectious lesions(AU)


Subject(s)
Humans , Male , Female , Pathology, Oral , Mouth Mucosa/pathology , Oral Medicine
2.
J. appl. oral sci ; 25(2): 217-226, Mar.-Apr. 2017. tab, graf
Article in English | LILACS, BBO | ID: biblio-841185

ABSTRACT

Abstract Objective The aim of this study was to compare the prevalence of periodontal pathogens, systemic inflammatory mediators and lipid profiles in type 1 diabetes children (DM) with those observed in children without diabetes (NDM), both with gingivitis. Material and methods Twenty-four DM children and twenty-seven NDM controls were evaluated. The periodontal status, glycemic and lipid profiles were determined for both groups. Subgingival samples of periodontal sites were collected to determine the prevalence of periodontal microorganisms by PCR. Blood samples were collected for IL-1-β, TNF-α and IL-6 analysis using ELISA kits. Results Periodontal conditions of DM and NDM patients were similar, without statistical differences in periodontal indices. When considering patients with gingivitis, all lipid parameters evaluated were highest in the DM group; Capnocytophaga sputigena and Capnocytophaga ochracea were more prevalent in the periodontal sites of DM children. “Red complex” bacteria were detected in few sites of DM and NDM groups. Fusobacterium nucleatum and Campylobacter rectus were frequently found in both groups. Similar levels of IL-1-β, TNF-α and IL-6 were detected in DM and NDM children. Conclusion Clinical and immunological profiles are similar between DM and NDM children. The presence of Capnocytophaga sputigena and Capnocytophaga ochracea were associated with gingivitis in DM children.


Subject(s)
Humans , Male , Female , Child , Adolescent , Periodontium/microbiology , Diabetes Mellitus, Type 1/microbiology , Diabetes Mellitus, Type 1/epidemiology , Gingivitis/microbiology , Gingivitis/epidemiology , Tooth, Deciduous/microbiology , Triglycerides/blood , Brazil/epidemiology , Capnocytophaga/isolation & purification , Enzyme-Linked Immunosorbent Assay , Periodontal Index , Polymerase Chain Reaction , Cholesterol/blood , Interleukin-6/blood , Tumor Necrosis Factor-alpha/blood , Statistics, Nonparametric , Dentition, Permanent , Diabetes Mellitus, Type 1/immunology , Interleukin-1beta/blood , Gingivitis/immunology
3.
Braz. dent. sci ; 20(2): 152-158, 2017. ilus, tab
Article in English | LILACS, BBO | ID: biblio-846454

ABSTRACT

The fibrous histiocytoma is a soft tissue neoplasm that affects the dermis and the subcutaneous tissue, rarely is found in the oral cavity and perioral regions, and is originated from the proliferation of fibroblasts and histiocytes. The objective of this paper is to report a case of Benign Fibrous Histiocytoma in a 30-year-old male patient, complaining of a painless nodule in the tongue for about six months. With diagnostic clinical hypotheses of Fibrous Hyperplasia, Neurofibroma, Traumatic Neuroma, Fibrous Histiocytoma, Granular Cell Tumor or Ectomesenchymal Chondromyxoid Tumor a excisional biopsy was performed. The histopathological examination revealed a non-encapsulated proliferation of spindle cells with some giant multinucleated cells in the periphery of the lesion. Immunohistochemical reactions were performed, staining only for vimentin in the spindle cells and for CD68 in the multinucleated giant cells. According to these characteristics, the final diagnosis was Benign Fibrous Histiocytoma. The correct diagnosis of spindle shaped cell neoplasia must be performed with the aid of histopathological analysis and immunohistochemistry, mainly because the morphological similarities with other benign and malignant lesions. (AU)


O Histiocitoma Fibroso é uma neoplasia de partes moles que acomete a derme e o tecido subcutâneo, raramente é encontrado na cavidade oral e regiões periorais, e tem origem a partir da proliferação de fibroblastos ou histiócitos. O objetivo deste artigo é relatar um caso de Histiocitoma Fibroso Benigno em um paciente masculino, 30 anos de idade, com um nódulo indolor, bem delimitado, com duração de cerca de seis meses, localizado no dorso anterior da língua. Com as hipóteses clínicas diagnósticas de Hiperplasia Fibrosa, Neurofibroma, Neuroma Traumático, Histiocitoma Fibroso, Tumor de Células Granulares e Tumor Condromixoide Ectomesenquimal uma biópsia foi realizada sob anestesia local e a lesão foi fixada em formol a 10% e enviada para análise histopatológica. O exame histopatológico revelou uma proliferação não-encapsulada de células fusiformes com algumas células gigantes multinucleadas na periferia da lesão. A marcação imunohistoquímica foi positiva para CD68 nas células gigantes multinucleadas e para vimentina nas células fusiformes. O diagnóstico final foi de Histiocitoma Fibroso Benigno. Para um diagnóstico correto, este deve ser feito correlacionando características clínicas, análise histopatológica e imunohistoquímica devido à similaridade microscópica do Histiocitoma Fibroso com outras lesões com aspecto fusocelular, assim como similaridade clínica com outras lesões benignas e malignas.(AU)


Subject(s)
Humans , Male , Adult , Fibroblasts , Histiocytes , Histiocytoma, Benign Fibrous
4.
Rev. bras. odontol ; 73(4): 348-352, Out.-Dez. 2016. ilus
Article in Portuguese | LILACS | ID: biblio-844056

ABSTRACT

Objetivo: relatar caso clínico de tumor odontogênico adenomatoide (TOA), enfatizando suas características e diagnósticos diferenciais. Relato de caso: paciente masculino, 16 anos, apresentando lesão radiolúcida, unilocular, associada ao dente 24 incluso. Sob as hipóteses de TOA, cisto dentígero, tumor odontogênico cístico calcificante e ameloblastoma unicístico, foi realizada biópsia excisional. Na microscopia, observou-se parênquima contendo estruturas tubulares e áreas semelhantes à roseta e cribriformes, estabelecendo o diagnóstico de TOA. Conclusão: o reconhecimento das características clínicas, radiográficas e histopatológicas do TOA é essencial para guiar o processo para se estabelecer o diagnóstico definitivo e, consequentemente, permitir o tratamento adequado do paciente.


Objective: to report a case of adenomatoid odontogenic tumor (AOT), highlighting its features and differential diagnosis. Case report: a 16-year-old male with a unilocular radiolucent lesion involving the unerupted 24th tooth. Considering AOT, dentigerous cyst, calcifying cystic odontogenic tumor, and unicystic ameloblastoma as the clinical diagnoses, an excisional biopsy was performed. Microscopic analysis revealed a parenchyma containing tubular structures and roset-like areas, establishing a diagnosis of AOT. Conclusion: the acknowledgement of clinical, radiographic, and microscopic features of AOT is essential to guide a definitive diagnosis and, as a consequence, to enable a suitable treatment of the patient.

5.
Rev. Assoc. Paul. Cir. Dent ; 68(1): 49-53, jan.-mar. 2014. ilus
Article in Portuguese | LILACS, BBO | ID: lil-715020

ABSTRACT

O objetivo deste trabalho é descrever o caso de um sialolito de grandes dimensões em glândula submandibular. Paciente do sexo feminino, leucoderma, 53 anos, procurou o cirurgião-dentista queixando-se de xerostomia, dor e inchaço na região de assoalho bucal, principalmente observado durante as refeições. O exame físico revelou uma tumefação em região submandibular esquerda, sensível a palpação, além de aumento de volume intra-oral firme, na região sublingual esquerda. Ao ordenhar a glândula submandibular, houve saída de pus. A radiografia oclusal inferior evidenciou extensa imagem radiopaca extensa, bem delimitada, cilíndrica e alongada. A associação dos exames clínicos e radiográficos levou ao diagnóstico de cálculo salivar. Foi realizada excisão cirúrgica da lesão sob anestesia local, com preservação da glândula submandibular. O exame anatomopatológico do cálculo revelou, na macroscopia, uma peça cirúrgica de consistência dura e cor amarela medindo 2,2 cm de diâmetro e, na microscopia, a presença de laminações concêntricas de material calcificado. A paciente encontra-se em acompanhamento há 2 anos e 8 meses, sem queixas de função glandular ou fluxo salivar, sem aumento de volume e exame radiográfico sem alterações. Apesar das grandes dimensões do sialolito, sua localização próxima à saída do dueto permitiu um tratamento conservador com bons resultados para a paciente.


This paper aims to describe a case of a large submandibular sialolith. A 53-year-old Caucasian female looked for for her dentist complaining of xerostomia, pain and swelling in the floor of the mouth, mainly observed during meals. The physical exam revealed a tender swelling on palpation in the left submandibular region, and also a firm intraoral swelling was detected in the left sublingual region. It was possible to draw pus from the submandibular gland. Mandibular occlusal radiography showed an extensive cylindrical and elongated, well-defined radiopaque image in the floor of the mouth. The association of clinical and radiographic findings led to the diagnosis of salivary calculus. The lesion was submitted to surgical excision under local anesthesia and the submandibular gland was maintened. Macroscopic analysis revealed a yellow and hard in consistency specimen, measuring 2.2 cm in length, and microscopic analysis revealed the presence of concentric laminations of calcified material associated with . The patient is being followed up for 2 years and 8 months, with no complaints of salivary flow or gland dysfunction, without gland swelling and no radiographic changes. Despite it being a large sialolith, its location near the exit of the duct allowed a conservative treatment with satisfactory aesthetic and functional results for the patient.


Subject(s)
Humans , Female , Middle Aged , Salivary Gland Calculi/surgery , Salivary Duct Calculi/surgery , Mouth Diseases , Salivary Gland Calculi/drug therapy , Mouth Floor/surgery , Mouth Floor/physiopathology
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